Metformin can also cause short-term side effects like stomach discomfort. What others have experienced may have nothing in common with what you do. Metformin is a medication developed to treat Type 2 diabetes that can also aid in weight loss. Nausea and gastrointestinal issues such as stomach pain, gas, bloating, and diarrhea are some of the most common side effects. This study is to estimate metformin related GI side effects in Indian population. You may report side effects to FDA at 1-800-FDA-1088. According to Dr. Elizabeth Halprin, clinical director of adult diabetes at Harvard's Joslin Diabetes Center, this low dose helps reduce gastrointestinal (GI) side effects. The more common side effects of metformin include: heartburn stomach pain nausea or vomiting bloating gas diarrhea constipation weight loss headache unpleasant metallic taste in mouth Lactic acidosis The most serious side effect metformin can cause is lactic acidosis. Common . This is called hypoglycaemia. RxList reports the most common side effects associated with metformin, occurring in more than 5 percent of patients using the drug, are diarrhea, nausea, vomiting, flatulence, diffuse lack of strength, headache, indigestion and abdominal discomfort. Common side effects of Glucophage include nausea, vomiting, gas, bloating, diarrhea, loss of appetite, weakness or lack of energy, respiratory tract infections, low levels of vitamin B-12, low blood glucose (hypoglycemia), constipation, indigestion, muscle pain, heartburn, and chills. Common side effects may include: low blood sugar; nausea, upset stomach; or; diarrhea. Like all medicines, metformin can cause side effects, although not everyone gets them. Treatment with metformin is, nevertheless, very often associated with gastrointestinal side effects and quality of life and treatment adherence is negatively affected in patients of type 2 diabetes. Here are some common metformin side effects like diarrhea and lactic acidosis. Other side effects. Here, I’ve a list of 25 most unpleasant metformin side effects that every patient on metformin should know. GI side effects of metformin are not so uncommon rather under reported or wrongly diagnosed as primary gastrointestinal disorder. glipizide), is the primary treatment for patients with type 2 diabetes. Or you can ask your pharmacist if your brand was included in the recall. I couldn’t concentrate on both and my weight and levels went up again. Often side effects improve as your body gets used to the new medicine. It is generally a safe and effective medication. Metformin side effects. Check with your doctor immediately if any of the following side effects occur: More common. Gastrointestinal Issues . Although these side-effects are not severe, they may lead to a condition known as lactic acidosis. In some cases, metformin leads to poor absorption of vitamin B-12. If this is the case for you, talk to your prescribing physician about potential side effects of metformin, as well as alternative treatments and medications. The most common side effects of metformin are related to gut complications and include upset stomach, nausea, vomiting, diarrhea, lightheadedness, or a metallic taste in the mouth . Call your doctor for medical advice about side effects. This is not a full list of side effects. Metformin can cause nausea, upset stomach, and diarrhea, particularly when you first start taking it. In fact, metformin has a boxed warning about this risk. Another study, “Metformin and Exercise in Type 2 Diabetes,” determined the effects of metformin on the metabolic response to submaximal exercise, the effect of exercise (relevant to activity patterns of type 2 diabetics) on plasma metformin concentrations, and the interaction between metformin and exercise on the response to a standardized meal. Drug information provided by: IBM Micromedex. It may even help with weight loss and lowering cholesterol. Metformin (Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet) is a medication prescribed to treat type 2 diabetes and the prevention of type 2 diabetes in patients who are at risk for type 2 diabetes. Some people using this medicine develop lactic acidosis, which can be fatal. These tummy troubles are the most common reason why people stop taking the medication. Side Effects. Metformin is one of the most prescribed drugs on the planet with over 120 million people taking it for diabetes management, but that doesn’t mean it’s the most popular.. The most common side effects of metformin are: Gas: The body naturally produces gas — and produces even more if you eat certain foods, particularly if you’ve just increased the amount of fiber in your diet. Get emergency medical help if you have signs of an allergic reaction to metformin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. 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